Synthesis of 14C-Labelled Propranolol Hydrochloride, 1-Isopropylamino-3- (1-naphthyloxy) propane-2-ol-1-14C Hydrochloride

Effect of propranolol and [4-(2-isopropylamino-1-hydroxyethyl) methanesulphonanilide hydrochloride] (MJ-1999) on pulmonary circulation.

While the pharmacological actions ofadrenergic beta receptor blocking agents specially those pertaining to cardiovascular system have been investigated in detail, there are only scattered reports dealing with their pulmonary vascular effects. Propranolol was shown to exert a variable effect on pulmonary arterial pressure and pulmonary vascular resistance (18). [4-( 2-isopropylamino-I-hydroxyeth...

Synthesis of 2-(4-methoxyphenyl)ethanol[ring-1-14C].

Propranolol Hydrochloride Extended-release Capsules, USP Rx only DESCRIPTION Propranolol hydrochloride, USP is a synthetic beta-adrenergic receptor-blocking agent chemically described as 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (+)-. Its molecular and structural formulae are: C16H21NO2

The inactive ingredients contained in propranolol hydrochloride extended-release capsules, USP are ethylcellulose, gelatin, hypromellose, microcrystalline cellulose, sodium lauryl sulfate and titanium dioxide. In addition, propranolol hydrochloride extended-release capsules, USP 60 mg, 120 mg, and 160 mg capsules contain FD&C Blue No. 1. Propranolol hydrochloride extendedrelease capsules, USP a...

Scalable synthesis of (1-cyclopropyl)cyclopropylamine hydrochloride

1-Cyclopropylcyclopropanecarboxylic acid (2), which is accessible on a large scale (900 mmol) from 1-bromo-1-cyclopropylcyclopropane (1) in 64% yield (89% on a 12.4 mmol scale), has been subjected to a Curtius degradation employing the Weinstock protocol to furnish the N-Boc-protected (1-cyclopropyl)cyclopropylamine 3 (76%). Deprotection of 3 with hydrogen chloride in diethyl ether gave the (1-...

Computational Investigation of the Effect of Changes in Halogenated on Factors in Nano-Carriers of 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochloride and C60

In this study, the drug combination of 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochloride or Procychelidine was applied on fullerene and its dual halogen derivatives were optimized in the position of carbon 62. In this study, using initial computation methods, the rate of participation of atomic orbitals and hybrid coefficients in adjacent adjacent atoms was ca...